综上所述，在生物学上,ＡＦＭ比ＳＴＭ更易阐明脱氧核糖核酸(ＤＮＡ)、蛋白质、多糖等生物大分子的结构,且有其独特的优势:生物大分子样品不需要覆盖导电薄膜;可在多种环境下直接实时观测;图像分辨率高;基底选择性强等。从Lindsay等人首次用ＡＦＭ获得ＤＮＡ分子的图像以来,ＡＦＭ便成为研究ＤＮＡ分子的重要工具.1992年,Ｂｕｓ ｔａｍａｎｔｅ等人用ＡＦＭ获得可重复的质粒ＤＮＡ分子图像.。
20世纪90年代以来,全球范围内掀起了纳米科学与技术革命.纳米技术是在纳米(10-9ｍ)和原子(约10-10ｍ)尺度(0.1～100ｎｍ)上研究物质(包括分子、原子)的特性及其相互作用,以及利用这些特性的多学科交叉的前沿科学与技术.ＡＦＭ在纳米技术中的应用必将极大地促进纳米技术不断发展.除物理、化学、生物等领域外,ＡＦＭ在微电子学、微机械学、新型材料、医学等领域都有着广泛的应用和巨大的应用前景.可以预言,在未来科学的发展中,ＡＦＭ将渗透到表面科学、材料科学、生命科学等各个科学技术领域中,它一定会成为我们的强大助手。
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