Elegant tour de force When the draft human genome sequence was published it was referred to as the blueprint... [more]

Have our dreams been shattered? RNA interference (RNAi) has revolutionized biology...[more]

 Spreading silence
How RNA interference (RNAi) spreads through plants and worms...[more]

 Ever-decreasing effects
Knockout and conditional mouse models allow investigators to...[more]

 Virus alert
RNA interference (RNAi) — the process in which double-stranded RNA (dsRNA)...[more]

 Down a hairpin
Short hairpin RNAs (shRNAs) — synthetic molecules modelled on small, non-coding...[more]

Killing the messenger: short RNAs that silence gene expression
Derek M. Dykxhoorn, Carl D. Novina and Phillip A. Sharp
Abstract | Full Text | PDF

 Exploring plant genomes by RNA-induced gene ilencing
Peter M. Waterhouse and Christopher A. Helliwell
Abstract | Full Text | PDF